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Pregnancy associated Plasma Protein A

Fasting

Not Required

Age Group

All Ages

Gender

Female

Get Reports

3-5 Days

Mode of Test

Home Collection, Center Visit

Test Includes

PAPP-A - a protein that is measured in a blood test to determine the chance of having a baby with birth defects. PAPPA has been used in prenatal genetic screening and studies of atherosclerosis. Women with low blood levels of PAPPA at 8 to 14 weeks of gestation have an increased risk of intrauterine growth restriction, trisomy 21, premature delivery, preeclampsia, and stillbirth. PAPPA is present in unstable atherosclerotic plaques, and circulating levels are elevated in acute coronary syndromes which may reflect the instability of the plaques. PAPPA may be a marker of unstable angina and acute myocardial infarction (heart attack).

Pregnancy associated Plasma Protein A

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Down syndrome (trisomy 21) or Edwards syndrome (trisomy 18).

Down syndrome-Decreased Muscle tone, Short neck, Small head, ear and mouth, Upward slanting eyes, White spots on the coloured part of the eyes, Wide short hands with short fingers, Single deep crease across the palm of hands. Edward Syndrome-Small abnormally shaped head, Small jaw and mouth, low set ears, Smooth rocker bottom feet, Heart and kidney problem, Breathing Problems, Bone abnormalities such as curved spine, Frequent infection of the lungs, severe learning disabilities.